LABORATORY OF BIOINORGANIC CHEMISTRY
PROF. DR. TATJANA N. PARAC-VOGT
Department of Chemistry, KU Leuven, Belgium
Welcome to the Laboratory of Bioinorganic Chemistry at KU Leuven, Belgium. In our group we exploit metal complexes as potential therapeutic drugs and catalysts for biologically relevant molecules.
Metals play an essential role in many biological processes, and are often found in the active sites of enzymes that catalyze a range of different reactions. A surprising number of therapeutic drugs also contain metals.
One of our lines of research is the design of polyoxometalate complexes as catalysts for some important biological reactions, such as the hydrolysis of phosphoester and peptide bonds. The second main research topic aims to design, develop, and characterize novel gadolinium based contrast agents with optical properties to make them suitable as potential therapeutic contrast agents for bimodal optical and magnetic resonance imaging.